In this proposal, we will combine the latest developments in tissue engineering (Prof Che Connon, Newcastle University), and the expertise of state of art analytical tools and food safety (Dr Romero, Fera Science Ltd). Novel scale-up and bioprocess intensification methodologies will also be explored (Dr Rios, UCL). UCL Biochemical Engineering would provide access to the latest perfusion bioreactors and microscale bioreactors among other systems. There is an opportunity to do a long internship (6 to 12 months) at UCL Biochemical Engineering, London UK.