This article reviews the core technologies underpinning cultured meat (CM) production, including cell line development, serum-free media, scaffold fabrication, and bioreactor design, with the goal of achieving large-scale, cost-effective production. By integrating these technologies, the field can address key challenges, such as high production costs and limited scalability. The review outlines a roadmap for achieving price parity with conventional meat by focusing on three main breakthroughs: engineering genetically stable cell lines to reduce reliance on expensive growth factors, utilizing plant-based alternatives to lower media and scaffold costs, and optimizing bioreactors to enable high-density cell cultures. The ultimate aim is to establish CM as a viable and sustainable alternative to traditional meat production.

Source: Scaling Cultured Meat: Challenges and Solutions for Affordable Mass Production – Gu – 2025 – Comprehensive Reviews in Food Science and Food Safety – Wiley Online Library

By Grégory Maubon

Leading Innovation ++ on the Field ++ with a Purpose => I used AI in cultivated meat industry to optimize bioreactor design and to dramatically improve the efficiency and quality of production. I developed high quality 3D imagery process in a biotechnological startup to disrupt the drug discovery methods.